I'd have to say, my "home" river is the Gunpowder up in Maryland. A beautiful stream, with healthy trout. But man, they are smart! The river gets a lot of pressure, so hooking in to a trout isn't always easy. I learned to fly-fish on this river, so needless to say, I got skunked quite a few times. That's alright though...nothing like a day on the water!
Here's a nice image I found of Gunpowder:
I'll post up some of my own pics soon!